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The liver X receptor agonist T0901317 reduces the inflammation of alveolar epithelial cells induced by polyhexamethylene guanidine through inhibition of the NFκB signaling pathway

BACKGROUND: As a kind of disinfectant, polyhexamethylene guanidine (PHMG) can cause pulmonary inflammation. In addition to liver X receptors (LXRs) playing an important role in cholesterol and lipid metabolism, it has also been found to be involved in inflammation in recent years. This article explo...

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Detalles Bibliográficos
Autores principales: Wei, Lutang, Guo, Yongzhong, Ding, Xiaoqian, Guo, Caihong, Ge, Nan, Ren, Dunqiang, Wang, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756235/
https://www.ncbi.nlm.nih.gov/pubmed/35071489
http://dx.doi.org/10.21037/atm-21-6501