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Endogenous Aβ induces osteoporosis through an mTOR-dependent inhibition of autophagy in bone marrow mesenchymal stem cells (BMSCs)

BACKGROUND: It has previously been suggested that Alzheimer’s disease (AD) and osteoporosis (OP) were related. However, the connection between these 2 disorders is poorly understood. This study aimed to investigate the relationship between amyloid β peptide (Aβ) and the osteoporotic deficit observed...

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Detalles Bibliográficos
Autores principales: Lin, Ye, Chen, Tianyu, Chen, Junjian, Fang, Yingying, Zeng, Canjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756236/
https://www.ncbi.nlm.nih.gov/pubmed/35071488
http://dx.doi.org/10.21037/atm-21-6427