Statistical methods for non-adherence in non-inferiority trials: useful and used? A systematic review

BACKGROUND: In non-inferiority trials with non-adherence to interventions (or non-compliance), intention-to-treat and per-protocol analyses are often performed; however, non-random non-adherence generally biases these estimates of efficacy. OBJECTIVE: To identify statistical methods that adjust for...

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Detalles Bibliográficos
Autores principales: Dodd, Matthew, Fielding, Katherine, Carpenter, James R, Thompson, Jennifer A, Elbourne, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Research Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756274/
https://www.ncbi.nlm.nih.gov/pubmed/35022173
http://dx.doi.org/10.1136/bmjopen-2021-052656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756274/
https://www.ncbi.nlm.nih.gov/pubmed/35022173
http://dx.doi.org/10.1136/bmjopen-2021-052656

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