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CRNDE silencing promotes apoptosis and enhances cisplatin sensitivity of colorectal carcinoma cells by inhibiting the Akt/mTORC1-mediated Warburg effect

Colorectal cancer (CRC) is one of the most prevalent gastrointestinal tumors worldwide, with a high mortality rate. The lncRNA colorectal neoplasia differentially expressed (CRNDE) is upregulated in CRC and is involved in regulating the apoptosis, proliferation, and drug sensitivity of CRC cells. Ho...

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Detalles Bibliográficos
Autores principales: Yang, Wenyu, Wang, Yanchun, Tao, Chunhui, Li, Yunhai, Cao, Shan, Yang, Xiqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756419/
https://www.ncbi.nlm.nih.gov/pubmed/35069879
http://dx.doi.org/10.3892/ol.2022.13190