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Therapeutic effect and mechanism of 4-phenyl butyric acid on renal ischemia-reperfusion injury in mice

The aim of the present study was to explore the effects and possible mechanism of 4-phenylbutyric acid (4-PBA) on renal ischemia-reperfusion injury (RIRI) in mice. A RIRI model of HK-2 cells was constructed using hypoxia/reoxygenation (H/R) treatment. Dexmedetomidine and 4-PBA were used to treat the...

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Detalles Bibliográficos
Autores principales: Wang, Xinlei, Zhang, Yang, Wuyun, Kun, Gong, Haixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756420/
https://www.ncbi.nlm.nih.gov/pubmed/35069825
http://dx.doi.org/10.3892/etm.2021.11067