Mutations in the helix αC of the catalytic domain from the EGFR affect its activity in cervical cancer cell lines

The EGFR is a protein that belongs to the ErbB family of tyrosine kinase receptors. The EGFR is often overexpressed in human carcinomas. Amplification of the EGFR gene and mutations in the EGFR tyrosine kinase domain occur in patients with cancer. In cervical cancer, the expression level of the EGFR...

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Detalles Bibliográficos
Autores principales: Valle-Mendiola, Arturo, Bustos-Rodríguez, Ricardo, Domínguez-Melendez, Vanihamin, Zerecero-Carreón, Octavio, Gutiérrez-Hoya, Adriana, Weiss-Steider, Benny, Soto-Cruz, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756430/
https://www.ncbi.nlm.nih.gov/pubmed/35069880
http://dx.doi.org/10.3892/ol.2022.13191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756430/
https://www.ncbi.nlm.nih.gov/pubmed/35069880
http://dx.doi.org/10.3892/ol.2022.13191

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