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A whole-exome case-control association study to characterize the contribution of rare coding variation to pancreatic cancer risk

Pancreatic cancer is a deadly disease that accounts for approximately 5% of cancer deaths worldwide, with a dismal 5-year survival rate of 10%. Known genetic risk factors explain only a modest proportion of the heritable risk of pancreatic cancer. We conducted a whole-exome case-control sequencing s...

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Detalles Bibliográficos
Autores principales: Yu, Yao, Chang, Kyle, Chen, Jiun-Sheng, Bohlender, Ryan J., Fowler, Jerry, Zhang, Di, Huang, Maosheng, Chang, Ping, Li, Yanan, Wong, Justin, Wang, Huamin, Gu, Jian, Wu, Xifeng, Schildkraut, Joellen, Cannon-Albright, Lisa, Ye, Yuanqing, Zhao, Hua, Hildebrandt, Michelle A.T., Permuth, Jennifer B., Li, Donghui, Scheet, Paul, Huff, Chad D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756505/
https://www.ncbi.nlm.nih.gov/pubmed/35047863
http://dx.doi.org/10.1016/j.xhgg.2021.100078