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A whole-exome case-control association study to characterize the contribution of rare coding variation to pancreatic cancer risk
Pancreatic cancer is a deadly disease that accounts for approximately 5% of cancer deaths worldwide, with a dismal 5-year survival rate of 10%. Known genetic risk factors explain only a modest proportion of the heritable risk of pancreatic cancer. We conducted a whole-exome case-control sequencing s...
Autores principales: | Yu, Yao, Chang, Kyle, Chen, Jiun-Sheng, Bohlender, Ryan J., Fowler, Jerry, Zhang, Di, Huang, Maosheng, Chang, Ping, Li, Yanan, Wong, Justin, Wang, Huamin, Gu, Jian, Wu, Xifeng, Schildkraut, Joellen, Cannon-Albright, Lisa, Ye, Yuanqing, Zhao, Hua, Hildebrandt, Michelle A.T., Permuth, Jennifer B., Li, Donghui, Scheet, Paul, Huff, Chad D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756505/ https://www.ncbi.nlm.nih.gov/pubmed/35047863 http://dx.doi.org/10.1016/j.xhgg.2021.100078 |
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