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Maternal effect genes: Update and review of evidence for a link with birth defects

Maternal effect genes (MEGs) encode factors (e.g., RNA) that are present in the oocyte and required for early embryonic development. Hence, while these genes and gene products are of maternal origin, their phenotypic consequences result from effects on the embryo. The first mammalian MEGs were ident...

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Detalles Bibliográficos
Autor principal: Mitchell, Laura E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756509/
https://www.ncbi.nlm.nih.gov/pubmed/35047854
http://dx.doi.org/10.1016/j.xhgg.2021.100067