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Maternal effect genes: Update and review of evidence for a link with birth defects
Maternal effect genes (MEGs) encode factors (e.g., RNA) that are present in the oocyte and required for early embryonic development. Hence, while these genes and gene products are of maternal origin, their phenotypic consequences result from effects on the embryo. The first mammalian MEGs were ident...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756509/ https://www.ncbi.nlm.nih.gov/pubmed/35047854 http://dx.doi.org/10.1016/j.xhgg.2021.100067 |