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Associations of genetic susceptibility to 16 cancers with risk of breast cancer overall and by intrinsic subtypes
Certain genetic variants are associated with risks of multiple cancers. We investigated breast cancer risk with overall genetic susceptibility to each of 16 other cancers. We constructed polygenic risk scores (PRS) for 16 cancers using risk variants identified by genome-wide association studies. We...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756518/ https://www.ncbi.nlm.nih.gov/pubmed/35047862 http://dx.doi.org/10.1016/j.xhgg.2021.100077 |