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Associations of genetic susceptibility to 16 cancers with risk of breast cancer overall and by intrinsic subtypes

Certain genetic variants are associated with risks of multiple cancers. We investigated breast cancer risk with overall genetic susceptibility to each of 16 other cancers. We constructed polygenic risk scores (PRS) for 16 cancers using risk variants identified by genome-wide association studies. We...

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Detalles Bibliográficos
Autores principales: Choi, Jungyoon, Jia, Guochong, Wen, Wanqing, Tao, Ran, Long, Jirong, Shu, Xiao-Ou, Zheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756518/
https://www.ncbi.nlm.nih.gov/pubmed/35047862
http://dx.doi.org/10.1016/j.xhgg.2021.100077