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Polygenic risk scores in the clinic: Translating risk into action

Polygenic risk scores (PRSs) are heralded as useful tools for risk stratification and personalized preventive care, but they are clinically useful only if they can be translated into action. The risk information conveyed by a PRS must be contextualized to enable this. Best practices are evolving but...

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Detalles Bibliográficos
Autores principales: Lewis, Anna C.F., Green, Robert C., Vassy, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756548/
https://www.ncbi.nlm.nih.gov/pubmed/35047839
http://dx.doi.org/10.1016/j.xhgg.2021.100047