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Synthesis, Bioactivity Assessment, and Molecular Docking of Non-sulfonamide Benzimidazole-Derived N-Acylhydrazone Scaffolds as Carbonic Anhydrase-II Inhibitors

[Image: see text] This research reports the synthesis of new benzimidazole-derived N-acylhydrazones (NAH), their characterization using various spectroscopic methods, and in vitro evaluation as potent carbonic anhydrase-II inhibitors. Among the target compounds (9–29), few showed higher inhibition t...

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Detalles Bibliográficos
Autores principales: Saadiq, Muhammad, Uddin, Ghias, Latif, Abdul, Ali, Mumtaz, Akbar, Nazia, Ammara, Ali, Sardar, Ahmad, Manzoor, Zahoor, Mohammad, Khan, Ajmal, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756595/
https://www.ncbi.nlm.nih.gov/pubmed/35036737
http://dx.doi.org/10.1021/acsomega.1c05362