Na(+)/Ca(2+) exchanger isoform 1 takes part to the Ca(2+)-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine

BACKGROUND: The cycad neurotoxin beta-methylamino-l-alanine (L-BMAA), one of the environmental trigger factor for amyotrophic lateral sclerosis/Parkinson-dementia complex (ALS/PDC), may cause neurodegeneration by disrupting organellar Ca(2+) homeostasis. Through the activation of Akt/ERK1/2 pathway,...

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Detalles Bibliográficos
Autores principales: Petrozziello, Tiziana, Boscia, Francesca, Tedeschi, Valentina, Pannaccione, Anna, de Rosa, Valeria, Corvino, Angela, Severino, Beatrice, Annunziato, Lucio, Secondo, Agnese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756626/
https://www.ncbi.nlm.nih.gov/pubmed/35022040
http://dx.doi.org/10.1186/s12964-021-00813-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756626/
https://www.ncbi.nlm.nih.gov/pubmed/35022040
http://dx.doi.org/10.1186/s12964-021-00813-z

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