Fully Validated, Multi-Kilogram cGMP Synthesis of MDMA

[Image: see text] MDMA is increasingly used in clinical research, but no cGMP process has yet been reported. We describe here the first fully validated cGMP synthesis of up to 5 kg (≈30 000 patient doses) of MDMA in a four-step process beginning with a noncontrolled starting material. The overall yi...

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Detalles Bibliográficos
Autores principales: Nair, Jay B., Hakes, Linda, Yazar-Klosinski, Berra, Paisner, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756783/
https://www.ncbi.nlm.nih.gov/pubmed/35036754
http://dx.doi.org/10.1021/acsomega.1c05520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756783/
https://www.ncbi.nlm.nih.gov/pubmed/35036754
http://dx.doi.org/10.1021/acsomega.1c05520

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