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Fully Validated, Multi-Kilogram cGMP Synthesis of MDMA
[Image: see text] MDMA is increasingly used in clinical research, but no cGMP process has yet been reported. We describe here the first fully validated cGMP synthesis of up to 5 kg (≈30 000 patient doses) of MDMA in a four-step process beginning with a noncontrolled starting material. The overall yi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756783/ https://www.ncbi.nlm.nih.gov/pubmed/35036754 http://dx.doi.org/10.1021/acsomega.1c05520 |