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Atomistic Model of Solute Transport across the Blood–Brain Barrier

[Image: see text] The blood–brain barrier remains a major roadblock to the delivery of drugs to the brain. While in vitro and in vivo measurements of permeability are widely used to predict brain penetration, very little is known about the mechanisms of passive transport. Detailed insight into inter...

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Detalles Bibliográficos
Autores principales: Jorgensen, Christian, Ulmschneider, Martin B., Searson, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757349/
https://www.ncbi.nlm.nih.gov/pubmed/35036773
http://dx.doi.org/10.1021/acsomega.1c05679