In Silico and In Vitro Studies for Benzimidazole Anthelmintics Repurposing as VEGFR-2 Antagonists: Novel Mebendazole-Loaded Mixed Micelles with Enhanced Dissolution and Anticancer Activity

[Image: see text] Cancer is a leading cause of death worldwide and its incidence is unfortunately anticipated to rise in the next years. On the other hand, vascular endothelial growth factor receptor 2 (VEGFR-2) is highly expressed in tumor-associated endothelial cells, where it affects tumor-promot...

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Detalles Bibliográficos
Autores principales: Elmaaty, Ayman Abo, Darwish, Khaled M., Chrouda, Amani, Boseila, Amira A., Tantawy, Mohamed A., Elhady, Sameh S., Shaik, Afzal B., Mustafa, Muhamad, Al-karmalawy, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757357/
https://www.ncbi.nlm.nih.gov/pubmed/35036753
http://dx.doi.org/10.1021/acsomega.1c05519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757357/
https://www.ncbi.nlm.nih.gov/pubmed/35036753
http://dx.doi.org/10.1021/acsomega.1c05519

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