Discovery of Potent Peptidomimetic Antagonists for Heterochromatin Protein 1 Family Proteins

[Image: see text] The heterochromatin protein 1 (HP1) sub-family of CBX chromodomains are responsible for the recognition of histone H3 lysine 9 tri-methyl (H3K9me3)-marked nucleosomal substrates through binding of the N-terminal chromodomain. These HP1 proteins, namely, CBX1 (HP1β), CBX3 (HP1γ), an...

Descripción completa

Detalles Bibliográficos
Autores principales: Lamb, Kelsey N., Dishman, Sarah N., Waybright, Jarod M., Engelberg, Isabelle A., Rectenwald, Justin M., Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Pearce, Kenneth H., James, Lindsey I., Frye, Stephen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757366/
https://www.ncbi.nlm.nih.gov/pubmed/35036738
http://dx.doi.org/10.1021/acsomega.1c05381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757366/
https://www.ncbi.nlm.nih.gov/pubmed/35036738
http://dx.doi.org/10.1021/acsomega.1c05381

Ejemplares similares