In Vitro, In Vivo, and In Silico Studies of Cumanin Diacetate as a Potential Drug against Trypanosoma cruzi Infection

[Image: see text] The sesquiterpene lactones cumanin, helenalin, and hymenin and their semisynthetic derivatives were evaluated against Trypanosoma cruzi epimastigotes. The cytotoxicity of the compounds was evaluated on murine splenocytes. Cumanin diacetate was one of the most active and selective c...

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Detalles Bibliográficos
Autores principales: Sánchez Alberti, Andrés, Beer, María F., Cerny, Natacha, Bivona, Augusto E., Fabian, Lucas, Morales, Celina, Moglioni, Albertina, Malchiodi, Emilio L., Donadel, Osvaldo J., Sülsen, Valeria P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757452/
https://www.ncbi.nlm.nih.gov/pubmed/35036760
http://dx.doi.org/10.1021/acsomega.1c05560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757452/
https://www.ncbi.nlm.nih.gov/pubmed/35036760
http://dx.doi.org/10.1021/acsomega.1c05560

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