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Prolonged oral antimicrobial administration prevents doxorubicin-induced loss of active intestinal stem cells

Acute intestinal mucositis is a common off-target effect of chemotherapy, leading to co-morbidities such as vomiting, diarrhea, sepsis, and death. We previously demonstrated that the presence of enteric bacteria modulates the extent of jejunal epithelial damage induced by doxorubicin (DXR) in mice....

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Detalles Bibliográficos
Autores principales: Sheahan, Breanna J, Theriot, Casey M, Cortes, Jocsa E., Dekaney, Christopher M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757478/
https://www.ncbi.nlm.nih.gov/pubmed/35012435
http://dx.doi.org/10.1080/19490976.2021.2018898