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Personalized therapy with peptide-based neoantigen vaccine (EVX-01) including a novel adjuvant, CAF®09b, in patients with metastatic melanoma

The majority of neoantigens arise from unique mutations that are not shared between individual patients, making neoantigen-directed immunotherapy a fully personalized treatment approach. Novel technical advances in next-generation sequencing of tumor samples and artificial intelligence (AI) allow fa...

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Detalles Bibliográficos
Autores principales: Mørk, Sofie Kirial, Kadivar, Mohammad, Bol, Kalijn Fredrike, Draghi, Arianna, Westergaard, Marie Christine Wulff, Skadborg, Signe Koggersbøl, Overgaard, Nana, Sørensen, Anders Bundgård, Rasmussen, Ida Svahn, Andreasen, Lars Vibe, Yde, Christina Westmose, Trolle, Thomas, Garde, Christian, Friis-Nielsen, Jens, Nørgaard, Nis, Christensen, Dennis, Kringelum, Jens Vindahl, Donia, Marco, Hadrup, Sine Reker, Svane, Inge Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757480/
https://www.ncbi.nlm.nih.gov/pubmed/35036074
http://dx.doi.org/10.1080/2162402X.2021.2023255