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Synthesis and bioactivities evaluation of oleanolic acid oxime ester derivatives as α-glucosidase and α-amylase inhibitors

Different oleanolic acid (OA) oxime ester derivatives (3a-3t) were designed and synthesised to develop inhibitors against α-glucosidase and α-amylase. All the synthesised OA derivatives were evaluated against α-glucosidase and α-amylase in vitro. Among them, compound 3a showed the highest α-glucosid...

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Detalles Bibliográficos
Autores principales: Deng, Xu-Yang, Ke, Jun-Jie, Zheng, Ying-Ying, Li, Dong-Li, Zhang, Kun, Zheng, Xi, Wu, Jing-Ying, Xiong, Zhuang, Wu, Pan-Pan, Xu, Xue-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757604/
https://www.ncbi.nlm.nih.gov/pubmed/35012401
http://dx.doi.org/10.1080/14756366.2021.2018682