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Second generation β-elemene nitric oxide derivatives with reasonable linkers: potential hybrids against malignant brain glioma

Elemene is a second-line broad-spectrum anti-tumour drug that has been used in China for more than two decades. However, its main anti-tumour ingredient, β-elemene, has disadvantages, including excessive lipophilicity and relatively weak anti-tumour efficacy. To improve the anti-tumour activity of β...

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Detalles Bibliográficos
Autores principales: Bai, Renren, Zhu, Junlong, Bai, Ziqiang, Mao, Qing, Zhang, Yingqian, Hui, Zi, Luo, Xinyu, Ye, Xiang-Yang, Xie, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757613/
https://www.ncbi.nlm.nih.gov/pubmed/35012394
http://dx.doi.org/10.1080/14756366.2021.2016734