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Bayesian Augmented Clinical Trials in TB Therapeutic Vaccination
We propose a Bayesian hierarchical method for combining in silico and in vivo data onto an augmented clinical trial with binary end points. The joint posterior distribution from the in silico experiment is treated as a prior, weighted by a measure of compatibility of the shared characteristics with...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757686/ https://www.ncbi.nlm.nih.gov/pubmed/35047949 http://dx.doi.org/10.3389/fmedt.2021.719380 |