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Embracing Mechanobiology in Next Generation Organ-On-A-Chip Models of Bone Metastasis

Bone metastasis in breast cancer is associated with high mortality. Biomechanical cues presented by the extracellular matrix play a vital role in driving cancer metastasis. The lack of in vitro models that recapitulate the mechanical aspects of the in vivo microenvironment hinders the development of...

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Detalles Bibliográficos
Autores principales: Slay, Ellen E., Meldrum, Fiona C., Pensabene, Virginia, Amer, Mahetab H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757701/
https://www.ncbi.nlm.nih.gov/pubmed/35047952
http://dx.doi.org/10.3389/fmedt.2021.722501