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Tumor Microenvironment in Oral Cancer Following Neoadjuvant Pembrolizumab: Preliminary Analysis of the Histopathologic Findings

Background: The tumor microenvironment (TME) of oral squamous cell carcinoma (OSCC) is associated with immune suppression, one of the pathways being the programmed death receptor 1 (PD-1) and its ligands (PD-L1/PD-L2). Checkpoint inhibitors of PD-1/PD-L1, like pembrolizumab, have been recently appro...

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Detalles Bibliográficos
Autores principales: Dobriyan, Alex, Gluck, Iris, Alon, Eran, Barshack, Iris, Yahalom, Ran, Vered, Marilena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757715/
https://www.ncbi.nlm.nih.gov/pubmed/35048002
http://dx.doi.org/10.3389/froh.2021.653104