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Increased Abundance of Tumour-Associated Neutrophils in HPV-Negative Compared to HPV-Positive Oropharyngeal Squamous Cell Carcinoma Is Mediated by IL-1R Signalling

The incidence of human papillomavirus (HPV)-associated cancer is increasing and HPV is now implicated in the aetiology of more than 60% of all oropharyngeal squamous cell carcinomas (OPSCC). In OPSCC, innate immune cells such as neutrophils and macrophages generally correlate with poor prognosis, wh...

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Detalles Bibliográficos
Autores principales: Al-Sahaf, Sarmad, Hendawi, Naeima B., Ollington, Bethany, Bolt, Robert, Ottewell, Penelope D., Hunter, Keith D., Murdoch, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757728/
https://www.ncbi.nlm.nih.gov/pubmed/35047989
http://dx.doi.org/10.3389/froh.2021.604565