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Cancer-Associated Fibroblasts in Oral Cancer: A Current Perspective on Function and Potential for Therapeutic Targeting

The role of the tumour microenvironement (TME) in cancer progression and resistance to therapies is now widely recognized. The most prominent non-immune cell type in the microenvironment of oral cancer (OSCC) is cancer-associated fibroblasts (CAF). Although CAF are a poorly characterised and heterog...

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Detalles Bibliográficos
Autores principales: Bienkowska, Kamila J., Hanley, Christopher J., Thomas, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757746/
https://www.ncbi.nlm.nih.gov/pubmed/35048030
http://dx.doi.org/10.3389/froh.2021.686337