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Modeling Cell Selectivity of Antimicrobial Peptides: How Is the Selectivity Influenced by Intracellular Peptide Uptake and Cell Density

Antimicrobial peptides (AMPs) are known to attack bacteria selectively over their host cells. Many attempts have been made to use them as a template for designing peptide antibiotics for fighting drug-resistant bacteria. A central concept in this endeavor is “peptide selectivity,” which measures the...

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Detalles Bibliográficos
Autores principales: Schefter, Bethany R., Nourbakhsh, Shokoofeh, Taheri-Araghi, Sattar, Ha, Bae-Yeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757749/
https://www.ncbi.nlm.nih.gov/pubmed/35047907
http://dx.doi.org/10.3389/fmedt.2021.626481