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Design and Validation of a Multi-Point Injection Technology for MR-Guided Convection Enhanced Delivery in the Brain

Convection enhanced delivery (CED) allows direct intracranial administration of neuro-therapeutics. Success of CED relies on specific targeting and broad volume distributions (V(D)). However, to prevent off-target delivery and tissue damage, CED is typically conducted with small cannulas and at low...

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Detalles Bibliográficos
Autores principales: Prezelski, Kayla, Keiser, Megan, Stein, Joel M., Lucas, Timothy H., Davidson, Beverly, Gonzalez-Alegre, Pedro, Vitale, Flavia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757778/
https://www.ncbi.nlm.nih.gov/pubmed/35047955
http://dx.doi.org/10.3389/fmedt.2021.725844