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miR-27a-3p regulates expression of intercellular junctions at the brain endothelium and controls the endothelial barrier permeability

BACKGROUND: The brain endothelial barrier permeability is governed by tight and adherens junction protein complexes that restrict paracellular permeability at the blood-brain barrier (BBB). Dysfunction of the inter-endothelial junctions has been implicated in neurological disorders such as multiple...

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Detalles Bibliográficos
Autores principales: Harati, Rania, Hammad, Saba, Tlili, Abdelaziz, Mahfood, Mona, Mabondzo, Aloïse, Hamoudi, Rifat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758013/
https://www.ncbi.nlm.nih.gov/pubmed/35025943
http://dx.doi.org/10.1371/journal.pone.0262152