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miR-27a-3p regulates expression of intercellular junctions at the brain endothelium and controls the endothelial barrier permeability
BACKGROUND: The brain endothelial barrier permeability is governed by tight and adherens junction protein complexes that restrict paracellular permeability at the blood-brain barrier (BBB). Dysfunction of the inter-endothelial junctions has been implicated in neurological disorders such as multiple...
Autores principales: | Harati, Rania, Hammad, Saba, Tlili, Abdelaziz, Mahfood, Mona, Mabondzo, Aloïse, Hamoudi, Rifat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758013/ https://www.ncbi.nlm.nih.gov/pubmed/35025943 http://dx.doi.org/10.1371/journal.pone.0262152 |
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