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Drosophila p53 isoforms have overlapping and distinct functions in germline genome integrity and oocyte quality control
p53 gene family members in humans and other organisms encode a large number of protein isoforms whose functions are largely undefined. Using Drosophila as a model, we find that a p53B isoform is expressed predominantly in the germline where it colocalizes with p53A into subnuclear bodies. It is only...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758136/ https://www.ncbi.nlm.nih.gov/pubmed/35023826 http://dx.doi.org/10.7554/eLife.61389 |