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insomniac links the development and function of a sleep-regulatory circuit

Although many genes are known to influence sleep, when and how they impact sleep-regulatory circuits remain ill-defined. Here, we show that insomniac (inc), a conserved adaptor for the autism-associated Cul3 ubiquitin ligase, acts in a restricted period of neuronal development to impact sleep in adu...

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Detalles Bibliográficos
Autores principales: Li, Qiuling, Jang, Hyunsoo, Lim, Kayla Y, Lessing, Alexie, Stavropoulos, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758140/
https://www.ncbi.nlm.nih.gov/pubmed/34908527
http://dx.doi.org/10.7554/eLife.65437