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Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation and imbalances in lipid metabolism in the liver. Although nuclear receptors (NRs) play a crucial role in hepatic lipid metabolism, the underlying mechanisms of NR regulation in NAFLD remain largely...

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Detalles Bibliográficos
Autores principales: Lee, Yo Han, Jang, Hyun-Jun, Kim, Sounkou, Choi, Sun Sil, Khim, Keon Woo, Eom, Hye-jin, Hyun, Jimin, Shin, Kyeong Jin, Chae, Young Chan, Kim, Hongtae, Park, Jiyoung, Park, Neung Hwa, Woo, Chang-Yun, Hong, Chung Hwan, Koh, Eun Hee, Nam, Dougu, Choi, Jang Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758141/
https://www.ncbi.nlm.nih.gov/pubmed/34964438
http://dx.doi.org/10.7554/eLife.70472