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Valsartan Regulates PI3K/AKT Pathways through lncRNA GASL1 to Improve Isoproterenol-Induced Heart Failure

OBJECTIVE: This study is aimed at determining the expression and function of the GASL1 and PI3K/AKT pathways in isoproterenol- (ISO-) induced heart failure (HF). To determine the moderating effect of valsartan (VAL) on the progression of ISO-induced HF and to elucidate the related mechanism. MATERIA...

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Detalles Bibliográficos
Autores principales: Zhou, Jian, Duan, Xiujuan, Wang, Jibing, Feng, Yunhong, Yuan, Jiangyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758289/
https://www.ncbi.nlm.nih.gov/pubmed/35035607
http://dx.doi.org/10.1155/2022/1447399