Cargando…

Valsartan Regulates PI3K/AKT Pathways through lncRNA GASL1 to Improve Isoproterenol-Induced Heart Failure

OBJECTIVE: This study is aimed at determining the expression and function of the GASL1 and PI3K/AKT pathways in isoproterenol- (ISO-) induced heart failure (HF). To determine the moderating effect of valsartan (VAL) on the progression of ISO-induced HF and to elucidate the related mechanism. MATERIA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Jian, Duan, Xiujuan, Wang, Jibing, Feng, Yunhong, Yuan, Jiangyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758289/ https://www.ncbi.nlm.nih.gov/pubmed/35035607 http://dx.doi.org/10.1155/2022/1447399

Ejemplares similares

LncRNA GASL1 is downregulated in chronic heart failure and regulates cardiomyocyte apoptosis
por: Deng, Haihong, et al.
Publicado: (2019)

A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity
por: Gasri-Plotnitsky, Lital, et al.
Publicado: (2017)

LncRNA GASL1 inhibits tumor growth in gastric carcinoma by inactivating the Wnt/β-catenin signaling pathway
por: Peng, Cao, et al.
Publicado: (2019)

Upgulation of lncRNA GASL1 inhibits atherosclerosis by regulating miR-106a/LKB1 axis
por: Rui, Xueqi, et al.
Publicado: (2023)

Long non-coding RNA GASL1 inhibits proliferation and invasion of osteosarcoma cells via modulation of the PI3K/Akt pathway
por: Gao, Feng, et al.
Publicado: (2019)

LncRNA GASL1 inhibits growth and promotes expression of apoptosis-associated proteins in prostate carcinoma cells through GLUT-1
por: Li, Zhiqin, et al.
Publicado: (2019)

Expression of a Novel Long Noncoding RNA (lncRNA), GASL1, is Downregulated in Patients with Intracranial Aneurysms and Regulates the Proliferation of Vascular Smooth Muscle Cells In Vitro
por: Man, Huibin, et al.
Publicado: (2019)

Oxytocin Protects Against Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting PI3K/AKT Pathway via a lncRNA GAS5/miR-375-3p/KLF4-Dependent Mechanism
por: Yang, Yuqiao, et al.
Publicado: (2021)

LncRNA DANCR upregulates PI3K/AKT signaling through activating serine phosphorylation of RXRA
por: Tang, Jianming, et al.
Publicado: (2018)

LncRNA LOXL1-AS1 Promotes the Proliferation and Metastasis of Medulloblastoma by Activating the PI3K/AKT Pathway
por: Gao, Ran, et al.
Publicado: (2018)

LncRNA TP73-AS1 promoted the progression of lung adenocarcinoma via PI3K/AKT pathway
por: Liu, Chunfeng, et al.
Publicado: (2019)

LncRNA LINC00961 regulates endothelial-mesenchymal transition via the PTEN-PI3K-AKT pathway
por: Hu, Jin-Xing, et al.
Publicado: (2022)

A novel lncRNA FPASL regulates fibroblast proliferation via the PI3K/AKT and MAPK signaling pathways in hypertrophic scar: FPASL regulates hypertrophic scar via the AKT and MAPK pathways
por: Ma, Fang, et al.
Publicado: (2022)

Sacubitril–valsartan in heart failure and multimorbidity patients
por: Rodil Fraile, Raquel, et al.
Publicado: (2018)

Boosting Akt Pathway by Rupatadine Modulates Th17/Tregs Balance for Attenuation of Isoproterenol-Induced Heart Failure in Rats
por: Ahmed, Lamiaa A., et al.
Publicado: (2021)

Muc5ac Production Inhibited by Decreased lncRNA H19 via PI3K/Akt/NF-kB in Asthma
por: Chen, Xu, et al.
Publicado: (2021)

Reply: Sacubitril/valsartan for Chagas' heart disease heart failure?
por: Bocchi, Edimar Alcides, et al.
Publicado: (2018)

lncRNA KCNQ1OT1 knockdown inhibits colorectal cancer cell proliferation, migration and invasiveness via the PI3K/AKT pathway
por: Duan, Qiaobin, et al.
Publicado: (2020)

LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway
por: Huang, Yanxia, et al.
Publicado: (2017)

lncRNA MALAT1 overexpression promotes proliferation, migration and invasion of gastric cancer by activating the PI3K/AKT pathway
por: Zhu, Kongxi, et al.
Publicado: (2019)

LncRNA MALAT1 Regulates the Cell Proliferation and Cisplatin Resistance in Gastric Cancer via PI3K/AKT Pathway
por: Dai, Qingqiang, et al.
Publicado: (2020)

Knockdown of lncRNA TDRG1 Inhibits Tumorigenesis in Endometrial Carcinoma Through the PI3K/AKT/mTOR Pathway
por: Sun, Ruimei, et al.
Publicado: (2019)

lncRNA Gm16410 Mediates PM(2).(5)-Induced Macrophage Activation via PI3K/AKT Pathway
por: Xu, Jingbin, et al.
Publicado: (2021)

LncRNA NCAL1 potentiates natural killer cell cytotoxicity through the Gab2-PI3K-AKT pathway
por: Niu, Chao, et al.
Publicado: (2022)

LncRNA LINC00460 facilitates the proliferation and metastasis of renal cell carcinoma via PI3K/AKT signaling pathway
por: Zhou, Feng-Juan, et al.
Publicado: (2022)

LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis
por: Wang, Sixuan, et al.
Publicado: (2022)

Practical guidance on the use of sacubitril/valsartan for heart failure
por: Sauer, Andrew J., et al.
Publicado: (2018)

Effectiveness of sacubitril–valsartan in cancer patients with heart failure
por: Martín‐Garcia, Ana, et al.
Publicado: (2020)

Haemodynamic effects of sacubitril/valsartan in advanced heart failure
por: Gentile, Piero, et al.
Publicado: (2022)

Growth differentiation factor 11 is involved in isoproterenol-induced heart failure
por: Zhang, Xiu-Jing, et al.
Publicado: (2019)

LncRNA ENST00113 promotes proliferation, survival, and migration by activating PI3K/Akt/mTOR signaling pathway in atherosclerosis
por: Yao, Xinliang, et al.
Publicado: (2018)

LncRNA‐LOC101928316 contributes to gastric cancer progression through regulating PI3K‐Akt‐mTOR signaling pathway
por: Li, Chengyun, et al.
Publicado: (2019)

Correction to: LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway
por: Huang, Yanxia, et al.
Publicado: (2020)

LncRNA TDRG1 Promotes Proliferation, Invasion and Epithelial-Mesenchymal Transformation of Osteosarcoma Through PI3K/AKT Signal Pathway
por: Huang, Yan, et al.
Publicado: (2020)

Silencing of lncRNA UCA1 inhibited the pathological progression in PCOS mice through the regulation of PI3K/AKT signaling pathway
por: Yang, Dongyong, et al.
Publicado: (2021)

lncRNA EZR-AS1 knockdown represses proliferation, migration and invasion of cSCC via the PI3K/AKT signaling pathway
por: Lu, Di, et al.
Publicado: (2021)

LncRNA LSINCT5/miR-222 regulates myocardial ischemia‑reperfusion injury through PI3K/AKT pathway
por: Tong, Xueying, et al.
Publicado: (2021)

LncRNA FENDRR in Carcinoma-Associated Fibroblasts Regulates the Angiogenesis of Oral Squamous Cell Carcinoma Through the PI3K/AKT Pathway
por: Xu, Yuming, et al.
Publicado: (2021)

Ablation of lncRNA Miat attenuates pathological hypertrophy and heart failure
por: Yang, Liu, et al.
Publicado: (2021)

Valsartan/Sacubitril in heart failure and hypotension: how, when and why
por: Scardovi, Angela Beatrice, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_c7rccefe2275gpe1nsj52k7r1g