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Effect of Rho-Kinase and Autophagy on Remote Ischemic Conditioning-Induced Cardioprotection in Rat Myocardial Ischemia/Reperfusion Injury Model

OBJECTIVE: Remote ischemic conditioning (RIC) is a cardioprotective method in ischemia/reperfusion (I/R) injury. This study investigated the mechanism of Rho-kinase-mediated autophagy in RIC. METHODS: Sixty male Sprague–Dawley rats were randomly divided into six groups: sham, I/R, RIC, I/R+fasudil,...

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Detalles Bibliográficos
Autores principales: Gao, Jie, Min, Feng, Wang, Shasha, Lv, Heng, Liang, Huan, Cai, Ben, Jia, Xianjie, Gao, Qin, Yu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758291/
https://www.ncbi.nlm.nih.gov/pubmed/35082919
http://dx.doi.org/10.1155/2022/6806427