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Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway

Intervertebral disc degeneration (IDD) is a degenerative disease that is characterized by decreased matrix synthesis and extra degradation, nucleus pulposus cells (NPCs) apoptosis, and infiltration of inflammatory factors. Aloin, a colored compound from aloe plants, has been shown to be effective ag...

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Detalles Bibliográficos
Autores principales: Chen, Taiqiu, Li, Pengfei, Qiu, Jincheng, Hu, Wenjun, Li, Shaoguang, Shi, Huihong, Qiu, Xianjian, Huang, Dongsheng, Gao, Wenjie, Liang, Anjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758297/
https://www.ncbi.nlm.nih.gov/pubmed/35035490
http://dx.doi.org/10.1155/2022/5865011