An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing asparagine

Voltage-gated sodium (Nav) channels play critical roles in propagating action potentials and otherwise manipulating ionic gradients in excitable cells. These channels open in response to membrane depolarization, selectively permeating sodium ions until rapidly inactivating. Structural characterizati...

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Detalles Bibliográficos
Autores principales: Choudhury, Koushik, Kasimova, Marina A., McComas, Sarah, Howard, Rebecca J., Delemotte, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758419/
https://www.ncbi.nlm.nih.gov/pubmed/34890580
http://dx.doi.org/10.1016/j.bpj.2021.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758419/
https://www.ncbi.nlm.nih.gov/pubmed/34890580
http://dx.doi.org/10.1016/j.bpj.2021.12.010

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