MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties

Alzheimer’s disease (AD) is the most common age-related form of dementia, associated with deposition of intracellular neuronal tangles consisting primarily of hyperphosphorylated microtubule-associated protein tau (p-tau) and extracellular plaques primarily comprising amyloid- β (Aβ) peptide. The p-...

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Detalles Bibliográficos
Autores principales: Chopra, Nipun, Wang, Ruizhi, Maloney, Bryan, Nho, Kwangsik, Beck, John S., Pourshafie, Naemeh, Niculescu, Alexander, Saykin, Andrew J., Rinaldi, Carlo, Counts, Scott E., Lahiri, Debomoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758483/
https://www.ncbi.nlm.nih.gov/pubmed/31942037
http://dx.doi.org/10.1038/s41380-019-0610-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758483/
https://www.ncbi.nlm.nih.gov/pubmed/31942037
http://dx.doi.org/10.1038/s41380-019-0610-2

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