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Aberrant role of ALK in tau proteinopathy through autophagosomal dysregulation

Proteinopathy in neurodegenerative diseases is typically characterized by deteriorating activity of specific protein aggregates. In tauopathies, including Alzheimer’s disease (AD), tau protein abnormally accumulates and induces dysfunction of the affected neurons. Despite active identification of ta...

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Detalles Bibliográficos
Autores principales: Park, Jisu, Choi, Hyunwoo, Kim, Young Doo, Kim, Seo-Hyun, Kim, Youbin, Gwon, Youngdae, Lee, Dong Young, Park, Sung-Hye, Heo, Won Do, Jung, Yong-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758490/
https://www.ncbi.nlm.nih.gov/pubmed/33452442
http://dx.doi.org/10.1038/s41380-020-01003-y