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Brain cells derived from Alzheimer’s disease patients have multiple specific innate abnormalities in energy metabolism

Altered energy metabolism has been implicated both in aging and the pathogenesis of late-onset Alzheimer’s disease (LOAD). However, it is unclear which anomalies are acquired phenotypes and which are inherent and predispose to disease. We report that neural progenitor cells and astrocytes differenti...

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Detalles Bibliográficos
Autores principales: Ryu, Woo-In, Bormann, Mariana K., Shen, Minqi, Kim, Dohoon, Forester, Brent, Park, Yeongwon, So, Jisun, Seo, Hyemyung, Sonntag, Kai-C., Cohen, Bruce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758493/
https://www.ncbi.nlm.nih.gov/pubmed/33863993
http://dx.doi.org/10.1038/s41380-021-01068-3