Cargando…
Impaired spike-gamma coupling of area CA3 fast-spiking interneurons as the earliest functional impairment in the App(NL-G-F) mouse model of Alzheimer’s disease
In Alzheimer’s disease (AD) the accumulation of amyloid-β (Aβ) correlates with degradation of cognition-relevant gamma oscillations. The gamma rhythm relies on proper neuronal spike-gamma coupling, specifically of fast-spiking interneurons (FSN). Here we tested the hypothesis that decrease in gamma...
Autores principales: | Arroyo-García, Luis Enrique, Isla, Arturo G., Andrade-Talavera, Yuniesky, Balleza-Tapia, Hugo, Loera-Valencia, Raúl, Alvarez-Jimenez, Laura, Pizzirusso, Giusy, Tambaro, Simone, Nilsson, Per, Fisahn, André |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758494/ https://www.ncbi.nlm.nih.gov/pubmed/34385602 http://dx.doi.org/10.1038/s41380-021-01257-0 |
Ejemplares similares
-
Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease
por: Arroyo-García, Luis Enrique, et al.
Publicado: (2023) -
Capsaicin-Induced Impairment of Functional Network Dynamics in Mouse Hippocampus via a TrpV1 Receptor-Independent Pathway: Putative Involvement of Na(+)/K(+)-ATPase
por: Balleza-Tapia, Hugo, et al.
Publicado: (2019) -
Timing to be precise? An overview of spike timing-dependent plasticity, brain rhythmicity, and glial cells interplay within neuronal circuits
por: Andrade-Talavera, Yuniesky, et al.
Publicado: (2023) -
TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro
por: Balleza-Tapia, Hugo, et al.
Publicado: (2018) -
Intranasal delivery of pro-resolving lipid mediators rescues memory and gamma oscillation impairment in App(NL-G-F/NL-G-F) mice
por: Emre, Ceren, et al.
Publicado: (2022)