Deep learning enables genetic analysis of the human thoracic aorta

Enlargement or aneurysm of the aorta predisposes to dissection, an important cause of sudden death. We trained a deep learning model to evaluate the dimensions of the ascending and descending thoracic aorta in 4.6 million cardiac magnetic resonance images from the UK Biobank. We then conducted genom...

Descripción completa

Detalles Bibliográficos
Autores principales: Pirruccello, James P., Chaffin, Mark D., Chou, Elizabeth L., Fleming, Stephen J., Lin, Honghuang, Nekoui, Mahan, Khurshid, Shaan, Friedman, Samuel N., Bick, Alexander G., Arduini, Alessandro, Weng, Lu-Chen, Choi, Seung Hoan, Akkad, Amer-Denis, Batra, Puneet, Tucker, Nathan R., Hall, Amelia W., Roselli, Carolina, Benjamin, Emelia J., Vellarikkal, Shamsudheen K., Gupta, Rajat M., Stegmann, Christian M., Juric, Dejan, Stone, James R., Vasan, Ramachandran S., Ho, Jennifer E., Hoffmann, Udo, Lubitz, Steven A., Philippakis, Anthony A., Lindsay, Mark E., Ellinor, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758523/
https://www.ncbi.nlm.nih.gov/pubmed/34837083
http://dx.doi.org/10.1038/s41588-021-00962-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758523/
https://www.ncbi.nlm.nih.gov/pubmed/34837083
http://dx.doi.org/10.1038/s41588-021-00962-4

Ejemplares similares