MZF1 mediates oncogene-induced senescence by promoting the transcription of p16(INK4A)

Oncogene induced senescence is a tumor suppressing defense mechanism, in which the cell cycle-dependent protein kinase (CDK) inhibitor p16(INK4A) (encoded by the CDKN2A gene) plays a key role. We previously reported that a transcriptional co-activator chromodomain helicase DNA binding protein 7 (CHD...

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Detalles Bibliográficos
Autores principales: Wu, Dan, Tan, Hua, Su, Weijun, Cheng, Dongmei, Wang, Guanwen, Wang, Juan, Ma, Ding A., Dong, George M., Sun, Peiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758531/
https://www.ncbi.nlm.nih.gov/pubmed/34773072
http://dx.doi.org/10.1038/s41388-021-02110-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758531/
https://www.ncbi.nlm.nih.gov/pubmed/34773072
http://dx.doi.org/10.1038/s41388-021-02110-y

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