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Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice

Endotoxemia triggers life-threatening immune and cardiovascular response that leads to tissue damage, multi-organ failure, and death. The understanding of underlying molecular mechanisms is still evolving. N6-methyladenosine (m6A) RNA modification plays key regulatory role in numerous biological pro...

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Detalles Bibliográficos
Autores principales: Dubey, Praveen K, Patil, Mallikarjun, Singh, Sarojini, Dubey, Shubham, Ahuja, Paras, Verma, Suresh Kumar, Krishnamurthy, Prasanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758538/
https://www.ncbi.nlm.nih.gov/pubmed/34581943
http://dx.doi.org/10.1007/s11010-021-04267-2