OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease

The generation of human oligodendrocyte progenitor cells (OPCs) may be therapeutically valuable for human demyelinating diseases such as multiple sclerosis. Here, we report the direct reprogramming of human somatic cells into expandable induced OPCs (iOPCs) using a combination of OCT4 and a small mo...

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Detalles Bibliográficos
Autores principales: Yun, Wonjin, Choi, Kyung-Ah, Hwang, Insik, Zheng, Jie, Park, Minji, Hong, Wonjun, Jang, Ah-Young, Kim, Jeong Hee, Choi, Wonji, Kim, Dae-Sung, Kim, In Yong, Kim, Yong Jun, Liu, Ying, Yoon, Byung Sun, Park, Gyuman, Song, Gwonhwa, Hong, Sunghoi, You, Seungkwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758684/
https://www.ncbi.nlm.nih.gov/pubmed/35027563
http://dx.doi.org/10.1038/s41536-021-00199-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758684/
https://www.ncbi.nlm.nih.gov/pubmed/35027563
http://dx.doi.org/10.1038/s41536-021-00199-z

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