Cargando…

Extension of human GCSF serum half-life by the fusion of albumin binding domain

Granulocyte colony stimulating factor (GCSF) can decrease mortality of patients undergo chemotherapy through increasing neutrophil counts. Many strategies have been developed to improve its blood circulating time. Albumin binding domain (ABD) was genetically fused to N-terminal end of GCSF encoding...

Descripción completa

Detalles Bibliográficos
Autores principales: Nikravesh, Fatemeh Yadavar, Shirkhani, Samira, Bayat, Elham, Talebkhan, Yeganeh, Mirabzadeh, Esmat, Sabzalinejad, Masoumeh, Aliabadi, Hooman Aghamirza Moghim, Nematollahi, Leila, Ardakani, Yalda Hosseinzadeh, Sardari, Soroush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758692/
https://www.ncbi.nlm.nih.gov/pubmed/35027593
http://dx.doi.org/10.1038/s41598-021-04560-6